The need to communicate hazards of chemicals to users is of the utmost importance. The widespread use of chemicals, the development of new chemicals, and the need to re-evaluate the hazards of pre-existing chemicals contribute to the importance of MSDS Compliance. In the United States, the Occupational Safety and Health Administration (OSHA) has created the Hazard Communication Standard (HCS) to mandate the use of a Material Safety Data Sheet (MSDS) and provide information to people who use, handle or store hazardous industrial chemicals.

The MSDS is used to convey the details on a material's identity, manufacturer information, hazard identity, emergency information, instructions on what to do if a hazardous situation has occurred, information on the prevention of hazardous situations, as well as other technical information. Recognizing the importance of this document, many other countries (e.g. the EU, Australia, Canada) have adopted the HCS into their own chemical safety initiatives.